DJS Antibodies (An AbbVie Company) - Research Scientist

DJS Antibodies (An AbbVie Company) - Research Associate

• A new role due to expansion
• Based at the vibrant research community of Oxford
• Comprehensive salary & benefits package
• Amazing career opportunities in a growing division with exceptional training

At DJS we are aspiring to create the next generation of antibody therapeutics, and in doing so, change the prognosis for patients living with life-changing conditions. We love working with people who share this vision and are passionate about pushing the boundaries of science to improve human health. Following our acquisition by AbbVie in October 2022 we are well positioned to use our technologies and expertise to pursue the toughest and most transformational targets. As we move forward our vision is to marry the biotech spirit of innovation and collaboration with big pharma expertise and experience to deliver life changing medicines for patients.

Job Objective:

The DJS-001 project is developing a first in class bispecific antibody to target myeloid cell-driven inflammatory disease. Through our novel biological insights, into the key drivers of myeloid cell recruitment and activation, we are developing a first in class therapeutic molecule capable of successfully targeting myeloid cell-driven inflammatory pathologies. which has exciting and wide-ranging applications in inflammatory disease and beyond.

The successful applicant will be a practical person who is organised, pays attention to detail, and efficiently gets the job done. Previous experience in a range of techniques is preferred but is not essential as training will be provided. At DJS we want to foster innovative scientists performing cutting edge science and as such a successful applicant will have many scientific career development opportunities, as a scientist or in laboratory/operations management. Furthermore, a successful applicant will be exposure to all aspects of R&D and the broader business at both DJS and within the wide AbbVie organisation.

Key Responsibilities:

• Bringing energy, enthusiasm and positivity to the company
• Maintenance of cell cultures
• Transient protein expression with mammalian cell lines
• Antibody purifications
• Performing critical laboratory experiments and analysing the data
• Molecular biology including (DNA preparation and purification, PCR, Cloning)
• Performing critical laboratory experiments and analysis to inform key decision making on DJS-001
• Work as a key member of the DJS-001 project team and contribute to strategic decision making
• Keeping up to date with developments in the literature in relation to all aspects of the DJS-001 program
• Day-to-day laboratory management as part of the team e.g. maintaining a safe and clean working laboratory environment, re-ordering laboratory consumables
• Establishing and maintaining quality sample archives
• Gathering, analysing and presenting data from a variety of sources to the wider team and organisation

• Critical and impartial review of self and peer generated laboratory data
• Maintenance of laboratory experimental records

Skills and Experience:

• A BSc of 2:1 level or higher with intercalated year in industrial/academic research and/or an MSc/MRes or higher degree with significant lab experience in a relevant discipline (such as Biology, Biochemistry, pathology, cell biology or Natural Sciences)
• Enthusiasm for and commitment to, drug development research and drug discovery
• Proven recent experience in (Mamalian cell culture, Molecular and biochemical techniques)
• Evidence of excellent organisational and interpersonal skis including
• Desirable skills (Running biological assays on primary cells and cell lines & good knowledge of statistics)

AbbVie is an equal opportunity employer including disability/vets. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a disabled veteran, recently separated veteran, Armed Forces service medal veteran or active duty wartime or campaign badge veteran or a person’s relationship or association with a protected veteran, including spouses and other family members, or any other protected group status. We will take affirmative action to employ and advance in employment qualified minorities, women, individuals with a disability, disabled veterans, recently separated veterans, Armed Forces service medal veterans or active-duty wartime or campaign badge veterans. The Affirmative Action Plan is available for viewing in the Human Resources office during regular business hours.